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Simplified theoretical analysis and numerical study on the dynamic behavior of FCP under blast loads
Chunfeng ZHAO, Xin YE, Avinash GAUTAM, Xin LU, Y. L. MO
《结构与土木工程前沿(英文)》 2020年 第14卷 第4期 页码 983-997 doi: 10.1007/s11709-020-0633-4
关键词: precast structure fabricated concrete panel blast resistance theory model empirical equation
Jun WU,Xuemei LIU
《结构与土木工程前沿(英文)》 2015年 第9卷 第3期 页码 323-340 doi: 10.1007/s11709-015-0301-2
关键词: high strength concrete (SHS) engineered cementitious composite interface blast test strain rate effect
Yonghui WANG, Ximei ZHAI
《结构与土木工程前沿(英文)》 2019年 第13卷 第6期 页码 1432-1445 doi: 10.1007/s11709-019-0566-y
关键词: blast loading curved steel-concrete-steel sandwich shell Pressure-Impulse diagram single-degree-of-freedom method finite element analysis
Simulation of blast induced crater in jointed rock mass by discontinuous deformation analysis method
Youjun NING, Xinmei AN, Jun YANG, Guowei MA,
《结构与土木工程前沿(英文)》 2010年 第4卷 第2期 页码 223-232 doi: 10.1007/s11709-010-0022-5
关键词: blast crater jointed rock mass explosion gas pressure discontinuous deformation analysis (DDA) method
Tae Un PAK; Guk Rae JO; Un Chol HAN
《结构与土木工程前沿(英文)》 2022年 第16卷 第8期 页码 1029-1039 doi: 10.1007/s11709-022-0861-x
关键词: wavelet analysis blast-induced vibration frequency characteristics underground excavation
Farhoud KALATEH
《结构与土木工程前沿(英文)》 2019年 第13卷 第1期 页码 15-37 doi: 10.1007/s11709-018-0465-7
关键词: air blast loading concrete dams finite element dam-reservoir interaction cavitation concrete damage model
Ismael Matino, Valentina Colla, Teresa A. Branca
《化学科学与工程前沿(英文)》 2018年 第12卷 第4期 页码 718-730 doi: 10.1007/s11705-018-1771-2
For improving wastewater quality, one of the dare of steelworks is reducing cyanide in wastewater of gas washing treatment of blast furnaces. Costs of existing treatments, stringent environmental regulations and changeable composition of water from gas treatment, have led to study how available treatments can be modified and to examine new ones. Ozonation is one of cyanide treatments, tested within a European project. A process model was set up with Aspen Plus®, to assess operating conditions and wastewater distinctive characteristics and to demonstrate treatment robustness. Process was modeled by theoretical reactors, taking into account all more affecting reactions. A genetic algorithm was exploited to find kinetic parameters of these reactions. After validation, the model was used to analyse scenarios, by considering also real contexts. Pilot tests were extended, process knowledge was enhanced and suggestions were obtained. To promote cyanide removal with ozone, temperature and pH values were 30°C and 10, respectively. With an ozone (mg/h)/water (L/h) ratio of 100 mg/L, batch mode ensure reaching cyanide regulation limit (0.2 mg/L) after maximum 4.5 h, if initial amount was less than 20 mg/L. Higher removal was obtained than in continuous mode due to constraints related to this last run. Higher wastewater contamination needed further time and more ozone.
关键词: blast furnace cyanide removal gas washing water modeling and simulation ozonation
Prevalence of antifolate drug resistance markers in in China
《医学前沿(英文)》 2022年 第16卷 第1期 页码 83-92 doi: 10.1007/s11684-021-0894-x
关键词: drug resistance antifolates molecular markers Plasmodium vivax China
Metagenomic analysis on resistance genes in water and microplastics from a mariculture system
《环境科学与工程前沿(英文)》 2022年 第16卷 第1期 页码 4-4 doi: 10.1007/s11783-021-1438-y
Microplastics existing widely in different matrices have been regarded as a reservoir for emerging contaminants. Mariculture systems have been observed to host microplastics and antibiotic resistance genes (ARGs). However, more information on proliferation of ARGs and metal resistance genes (MRGs) in mariculture system at the presence of microplastics is needed.
关键词: Antibiotic resistance genes Metal resistance genes Metagenomic analysis Microplastics Mariculture
Taking advantage of drug resistance, a new approach in the war on cancer
null
《医学前沿(英文)》 2018年 第12卷 第4期 页码 490-495 doi: 10.1007/s11684-018-0647-7
Identification of the driver mutations in cancer has resulted in the development of a new category of molecularly targeted anti-cancer drugs. However, as was the case with conventional chemotherapies, the effectiveness of these drugs is limited by the emergence of drug-resistant variants. While most cancer therapies are given in combinations that are designed to avoid drug resistance, we discuss here therapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drug resistance. This approach is based on notion that drug resistance comes at a fitness cost to the cancer cell that can be exploited for therapeutic benefit. We discuss the development of sequential drug therapies in which the first therapy is not given with curative intent, but to induce a major new sensitivity that can be targeted with a second drug that selectively targets the acquired vulnerability. This concept of collateral sensitivity has hitherto not been used on a large scale in the clinic and holds great promise for future cancer therapy.
关键词: cancer drug resistance genetic screens senescence targeted therapy
Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors
《医学前沿(英文)》 2022年 第16卷 第5期 页码 701-713 doi: 10.1007/s11684-022-0951-0
关键词: acquired resistance EGFR inhibitor apoptosis lung cancer
Transmission of antibiotic resistance genes in agroecosystems: an overview
Jizheng HE, Zhenzhen YAN, Qinglin CHEN
《农业科学与工程前沿(英文)》 2020年 第7卷 第3期 页码 329-332 doi: 10.15302/J-FASE-2020333
The use of antibiotics in human medicine and animal husbandry has resulted in the continuous release of antibiotics into the environment, which imposes high selection pressure on bacteria to develop antibiotic resistance. The spread and aggregation of antibiotic resistance genes (ARGs) in multidrug-resistant pathogens is one of the most intractable clinical challenges. Numerous studies have been conducted to profile the patterns of ARGs in agricultural ecosystems, as this is closely related to human health and wellbeing. This paper provides an overview of the transmission of ARGs in agricultural ecosystems resulting from the application of animal manures and other organic amendments. The future need to control and mitigate the spread of antibiotic resistance in agricultural ecosystems is also discussed, particularly from a holistic perspective, and requires multiple sector efforts to translate fundamental knowledge into effective strategies.
关键词: agroecosystem antibiotic resistance public health soil-plant system
《环境科学与工程前沿(英文)》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1342-x
• SMX addition had negative effect on acetoclastic methanogens in mesophilic AD.
关键词: Pig manure Antibiotics Anaerobic digestion Resistance genes Microbial community
Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden
《环境科学与工程前沿(英文)》 2019年 第13卷 第3期 doi: 10.1007/s11783-019-1124-5
Extracellular DNA structure damaged by chlorination was characterized. Integrity of extracellular ARG genetic information after chlorination was determined. Typical chlorine doses will likely effectively diminish extracellular DNA and ARGs. Plasmid DNA/ARGs were less readily broken down than genomic DNA. The Bioanalyzer methodology effectively documented damage incurred to DNA.
关键词: Antibiotic resistance Antibiotic resistance genes (ARGs) Extracellular DNA/ARGs Chlorination
Insulin resistance and the metabolism of branched-chain amino acids
null
《医学前沿(英文)》 2013年 第7卷 第1期 页码 53-59 doi: 10.1007/s11684-013-0255-5
Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently causes serious health problems with an increased risk of several common metabolic disorders. IR related metabolic disturbance is not restricted to carbohydrates but impacts global metabolic network. Branched-chain amino acids (BCAAs), namely valine, leucine and isoleucine, are among the nine essential amino acids, accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformed amino acids required by mammals. The BCAAs are particularly responsive to the inhibitory insulin action on amino acid release by skeletal muscle and their metabolism is profoundly altered in insulin resistant conditions and/or insulin deficiency. Although increased circulating BCAA concentration in insulin resistant conditions has been noted for many years and BCAAs have been reported to be involved in the regulation of glucose homeostasis and body weight, it is only recently that BCAAs are found to be closely associated with IR. This review will focus on the recent findings on BCAAs from both epidemic and mechanistic studies.
关键词: branched-chain amino acids leucine isoleucine valine insulin resistance
标题 作者 时间 类型 操作
Simplified theoretical analysis and numerical study on the dynamic behavior of FCP under blast loads
Chunfeng ZHAO, Xin YE, Avinash GAUTAM, Xin LU, Y. L. MO
期刊论文
Performance of soft-hard-soft (SHS) cement based composite subjected to blast loading with consideration
Jun WU,Xuemei LIU
期刊论文
Development of dimensionless P-I diagram for curved SCS sandwich shell subjected to uniformly distributed blast
Yonghui WANG, Ximei ZHAI
期刊论文
Simulation of blast induced crater in jointed rock mass by discontinuous deformation analysis method
Youjun NING, Xinmei AN, Jun YANG, Guowei MA,
期刊论文
Prediction of characteristic blast-induced vibration frequency during underground excavation by using
Tae Un PAK; Guk Rae JO; Un Chol HAN
期刊论文
Dynamic failure analysis of concrete dams under air blast using coupled Euler-Lagrange finite element
Farhoud KALATEH
期刊论文
Extension of pilot tests of cyanide elimination by ozone from blast furnace gas washing water through
Ismael Matino, Valentina Colla, Teresa A. Branca
期刊论文
Transmission of antibiotic resistance genes in agroecosystems: an overview
Jizheng HE, Zhenzhen YAN, Qinglin CHEN
期刊论文
swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance
期刊论文
Degradation of extracellular genomic, plasmid DNA and specific antibiotic resistance genes by chlorination
Menglu Zhang, Sheng Chen, Xin Yu, Peter Vikesland, Amy Pruden
期刊论文